Association between sperm mitochondrial ND2 gene variants and total fertilization failure
نویسندگان
چکیده
منابع مشابه
Total fertilization failure and idiopathic subfertility
BACKGROUND To gain more insight in whether failure of intrauterine insemination (IUI) treatment in patients with idiopathic subfertility could be related to diminished fertilization, the aim of this study is to compare the fertilization of an initial IVF procedure after six cycles of IUI and the fertilization of an initial IVF procedure without preceding IUI cycles in couples with idiopathic su...
متن کاملAnalysis of 232 total fertilization failure cycles during intracytoplasmic sperm injection
BACKGROUND The intracytoplasmic sperm injection procedure ending with total fertilization failure is very distressfull event for both the clinician and the patient. OBJECTIVE The aim of this study was to identify independent factors which could be used to identify total fertilization failure before the day of intracytoplasmic sperm injection. MATERIALS AND METHODS This was a retrospective s...
متن کاملComparison between intracytoplasmic sperm injection and in-vitro fertilization (IVF) with high insemination concentration after total fertilization failure in a previous IVF attempt.
The aim of this prospective study was to evaluate whether couples with total fertilization failure in a previous in-vitro fertilization (IVF) attempt should be offered an additional IVF treatment with elevated insemination concentration or should be treated with intracytoplasmic sperm injection (ICSI). In 23 cycles 228 sibling metaphase II (MII) oocytes were randomly divided: 143 and 85 oocytes...
متن کاملanalysis of 232 total fertilization failure cycles during intracytoplasmic sperm injection
abstract background: the intracytoplasmic sperm injection procedure ending with total fertilization failure is very distressfull event for both the clinician and the patient. objective: the aim of this study was to identify independent factors which could be used to identify total fertilization failure before the day of intracytoplasmic sperm injection. materials and methods: this was a retrosp...
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BACKGROUND Mitochondrial ND gene, which encodes NADH dehydrogenase, is the first enzyme of the mitochondrial electron transport chain. Leigh syndrome, a neurodegenerative disease caused by mutation in the ND2 gene (T4681C), is associated with bilateral symmetric lesions in basal ganglia and subcortical brain regions. Therefore, it is of interest to analyze mitochondrial DNA to glean information...
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ژورنال
عنوان ژورنال: Systems Biology in Reproductive Medicine
سال: 2018
ISSN: 1939-6368,1939-6376
DOI: 10.1080/19396368.2018.1447616